Diethylene glycol bis(p-toluenesulfonate)
CAS No. 7460-82-4
Diethylene glycol bis(p-toluenesulfonate)( Diethylene glycol di(p-toluenesulfonate) | Bis-Tos-PEG2 )
Catalog No. M26939 CAS No. 7460-82-4
Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
1G | 32 | In Stock |
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Biological Information
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Product NameDiethylene glycol bis(p-toluenesulfonate)
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NoteResearch use only, not for human use.
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Brief DescriptionDiethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionDiethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsDiethylene glycol di(p-toluenesulfonate) | Bis-Tos-PEG2
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PathwayOthers
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TargetOther Targets
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RecptorHuman Endogenous Metabolite| phosphoglucose isomerase (PGI)
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Research Area——
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Indication——
Chemical Information
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CAS Number7460-82-4
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Formula Weight414.49
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Molecular FormulaC18H22O7S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (241.26 mM)
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SMILESCc1ccc(cc1)S(=O)(=O)OCCOCCOS(=O)(=O)c1ccc(C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gaitonde MK, et al. Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J Neurochem. 1989 May;52(5):1348-52.
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