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Diethylene glycol bis(p-toluenesulfonate)

CAS No. 7460-82-4

Diethylene glycol bis(p-toluenesulfonate)( Diethylene glycol di(p-toluenesulfonate) | Bis-Tos-PEG2 )

Catalog No. M26939 CAS No. 7460-82-4

Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Diethylene glycol bis(p-toluenesulfonate)
  • Note
    Research use only, not for human use.
  • Brief Description
    Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    Diethylene glycol di(p-toluenesulfonate) | Bis-Tos-PEG2
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Human Endogenous Metabolite| phosphoglucose isomerase (PGI)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    7460-82-4
  • Formula Weight
    414.49
  • Molecular Formula
    C18H22O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 100 mg/mL (241.26 mM)
  • SMILES
    Cc1ccc(cc1)S(=O)(=O)OCCOCCOS(=O)(=O)c1ccc(C)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gaitonde MK, et al. Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J Neurochem. 1989 May;52(5):1348-52.
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